Her debut album, This Is the Life, was released on 30 July 2007 and has sold more than 2.5 million copies. Her first single, "Poison Prince", was released on 7 May 2007. She played shows at music festivals such as Glastonbury, Hyde Park, T in the Park, and V festival. Amy is signed to record company Vertigo. Amy's vocal range is contralto.
Macdonald started playing on stage acoustic gigs at 15. Her influences include Travis, The Killers, Pete Doherty, and Bruce Springsteen. After several shows in mainland Europe, Macdonald played at festivals such as V Fest during the summer of 2008.
In 2008, Macdonald was engaged to Falkirk striker Steve Lovell.
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