He was diagnosed with a brain tumor in 2001 but recovered. In October 2011, Murphy stated that the tumor had returned but that it was non-cancerous and that it was being treated pharmacologically. He is working on a tribute album to Death founder Chuck Schuldiner who died from pneumonia, caused by complications of his treatment for a brain tumor. He is also producing Deron Miller's band World Under Blood. He also completed production of the industrial death metal band Daath's second album, The Hinderers, which was released on Roadrunner Records, and Lazarus A.D.'s debut album The Onslaught released on Metal Blade Records. He has also performed as a touring guitarist for Agent Steel, and in Hallows Eve in 1988.
In addition to playing guitar, Murphy operates a recording studio, SafeHouse Production, where he has mixed and produced albums for other bands. He has also contributed lessons to Guitar Player magazine.
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