Lanegan has also collaborated with various artists and bands throughout his career, including with Kurt Cobain of Nirvana prior to the group's breakout success with their album, Nevermind, recording an unreleased album of songs by the blues singer, Lead Belly. Following the dissolution of The Screaming Trees in 2000, he became a member of Queens of the Stone Age and is featured on four of the band's albums--Rated R (2000), Songs for the Deaf (2002), Lullabies to Paralyze (2005) and ...Like Clockwork (2013). Lanegan also formed The Gutter Twins with Greg Dulli in 2003, released three collaboration albums with former Belle and Sebastian singer Isobel Campbell, and contributed to releases by Melissa Auf der Maur, Martina Topley Bird, Creature with the Atom Brain, Moby, Bomb the Bass, Soulsavers and Mad Season.
Lanegan has a distinctive baritone voice that has been described "as scratchy as a three-day beard yet as supple and pliable as moccasin leather" and compared to Tom Waits.
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