Can you spot what’s strange about this new ‘Vanity Fair’ cover?

Reese Witherspoon and Oprah Winfrey have responded to the furore

The latest issue of Vanity Fair has sparked a big online discussion over what appear to be multiple Photoshop errors.

The magazine’s annual Hollywood cover features a star-studded line up that includes the likes of Oprah Winfrey, Jessica Chastain, Reese Witherspoon, Tom Hanks and Robert DeNiro. You can see the full fold-out cover in the image below.

After revealing the cover, readers swiftly took to Twitter to point out that Reese Witherspoon appears to have three legs in the photo.

While Vanity Fair claimed that Witherspoon’s supposed third leg was just “the lining of her dress”, people spotted a further apparent mistake in a separate photo, which appeared to depict Oprah Winfrey with three hands.

That photo has since been removed from the Vanity Fair website.

Both Witherspoon and Winfrey have taken to social media to make light of the situation. “Well… I guess everybody knows now… I have 3 legs,” Witherspoon tweeted, adding: “I hope you can still accept me for who I am and I will never apologize for snuggling @Oprah .. if you get the opportunity, I highly recommend it”.

Winfrey replied: “I accept your 3d leg. As I know you accept my 3d hand”.

It has been confirmed that James Franco was digitally removed from the cover following sexual misconduct accusations facing the actor, which he disputes.

“We made a decision not to include James Franco on the Hollywood cover once we learned of the misconduct allegations against him”, Vanity Fair confirmed in a statement.