Leonardo DiCaprio and Martin Scorsese reunite for film about infamous Chicago serial killer

The film will be based on Erik Larson's book 'The Devil In The White City'

Leonardo DiCaprio and Martin Scorsese are to reunite for a new movie about a notorious Chicago serial killer.

DiCaprio will play Dr HH Holmes, who is estimated to have killed up to 200 people from a hotel he constructed at the 1893 World’s Fair in the city. Holmes’s so-called “murder castle” had its own gas chamber, crematorium and dissecting table where his victims, mainly young females, would be murdered.

The film is based on Erik Larson’s acclaimed 2003 book The Devil In The White City: Murder, Magic And Madness At The Fair That Changed America, which offers a novelistic take on real-life events.

Scorsese will direct from a script by Billy Ray (Flightplan, The Hunger Games), while DiCaprio will serve as a producer, Deadline reports. The actor is understood to have wanted to turn Larson’s book into a movie for some time.

This will be the sixth big screen collaboration between DiCaprio and Scorsese, who previously teamed up for Gangs Of New York, The Aviator, The Departed, Shutter Island and The Wolf Of Wall Street. DiCaprio earned Oscar nominations for his performances in both The Aviator and The Wolf Of Wall Street.