Guy Pearce and Kelly MacDonald will star in the film
Steve Buscemi is to direct a new adaptation of the William S Burroughs novel Queer.
The Boardwalk Empire star will helm the new film, from a script written by Oren Moverman, according to Paste.
Guy Pearce, Ben Foster and Kelly MacDonald have all joined the cast, and shooting is expected to start when Buscemi wraps filming on the next series of his HBO gangster TV drama.
The story follows a character named William Lee, who lives in Mexico among expatriates in the 1940s. Craving human contact, Lee tries to seduce another character called Eugene Allerton. Initially disinterested in Lee’s advances, but Allerton becomes his reluctant lover as they travel to Ecuador in search of a drug called Yage.
Buscemi won the Best Actor Golden Globe Award this year for his role of Enoch ‘Nucky’ Thompson in Boardwalk Empire.