Fans are being encourage to assemble at the landmark on June 15, the day before the first show.
The singalong will last from 6pm until 9pm on the day, and all those wishing to exercise their vocals must register with Muselive.com to attend.
In March, the site will poll fans to choose which ten songs they will be singing.
For more information and to register go to Trafalgarmusefans.com.
The Muse singalong is being held in aid of Devon charity The Helen Foundation.
For the inside story of how Muse managed to pull off the first ever gigs at the new stadium and what they have planned for June 16 and 17, get next week’s issue of NME, on UK newsstands from February 28.
Meanwhile the band have added extra tickets for the stadium shows. To check ticket availability and get all the latest listings, go to NME.COM/GIGS, now.