Ditko died in New York at the age of 90, police say
Police say he was found unresponsive at a flat in Manhattan, New York, on 29 June and was later declared dead by paramedics at the scene.
Fans have taken to Twitter to pay tribute to the artist.
Author Neil Gaiman tweeted: “Steve Ditko was true to his own ideals. He saw things his own way, and he gave us ways of seeing that were unique. Often copied. Never equalled. I know I’m a different person because he was in the world.”
Filmaker Edgar Wright wrote: “RIP to comic book legend Steve Ditko, beyond influential on countless planes of existence. He never truly profited from his comic creations that have lasted for decades, but his work will never be forgotten.”
Ditko worked with Marvel Comics throughout the 1960s and his work with future Marvel CEO Stan Lee lead to the creation of two of the company’s most iconic characters – Spider-Man and Doctor Strange.
While Lee is believed to have come up with the idea of a man with spider-like powers, Ditko is credited with creating his famous red and blue suit.
Ditko parted ways with Marvel in 1966, allegedly after a disagreement with Lee, and went on to work with DC Comics, where he created the superhero The Creeper.