First up: it's lo-fi London dubstep man James Blake. His self-titled debut album is a "stunning hybrid of sparse electronics that's not afraid to let one note chime or thud alone", according to Laura Snapes in the new issue. Hear James Blake on MySpace.
Punk tearaways The Vaccines have been hyped more than any other over the last few weeks and months, and they seem to split opinion right down the middle, like any decent band should. Download a track from the Radar blog and wade into the debate.
Essex pop starlet Jessie J has already claimed a place on the BBC Sound Of 2011 poll, as well as bagging the coveted Critics Choice spot for this year's Brit Awards, and been hailed as "the best singer in the world" by Justin Timberlake. Her NME nod completes the set. Find out what all the fuss is about on her MySpace.
Anna Calvi is set to storm 2011 with her theatric PJ Harvey-esque songwriting. Brian Eno and Nick Cave are already fans - read her Radar profile to find out why.
Fans of MGMT and Passion Pit may get very excited indeed as The Naked And Famous shift into the public's conciousness this year. If you like exuberant pop and shamelessy widescreen choruses, go say hi on MySpace.
Self-styled "gritpop" band Brother have big and bold aims. They played an early show at the Met bar of all places and have Glastonbury's main stage in their sights. Prepared to accept nothing less than world domination, they're after the Oasis crown. Check them out on Facebook.
Scandanavian band Niki And The Dove purvey a shimmering goth-tinged electronica for fans of Bat For Lashes or Fever Ray. Watch their debut video on the NME Radar blog.
Jamie Woon is a graduate of the Brit School and a protegé of Burial, and crafts beautiful post-dubstep like James Blake. Grab a free track on the NME Radar blog.
Big Deal made their NME debut back in September on the Daily Download (where you can download a free MP3). The duo exhume the ghost of Big Star and their fragile acoustic pop is set to make them a, yep, big deal.
Grouplove featured in our summer round-up of 2010's top new bands, and are going to dominate 2011, thanks to their way with a big indie singalong chorus.
One of the best-looking new prospects for 2011 (not that looks come into it, Brother will tell you that): Oh Land. The Scandanavian ballet dancer turned pop starlet is looking to give Lykke Li a run for her money. Check her out on Myspace now.
Fan of The Beach Boys? Love Animal Collective? Get yourself a fix of Fixers then - the Oxford psychedelic warriors are the next to take up the torch. Fall under their spell on MySpace now.
Mona have been dubbed "princes of Leon", but the Nashville four plough their own distinctive furrow of southern-tinged rock and roll. Download a track on the NME Radar blog.
Spark - aka 18-year-old Walthamstow girl Jess Morgan - is another Brit School graduate that's ditched the Kate Melua avenue for a more glam punk route. It's paid off - she's already toured with Marina and looks set to own this year. Read a full profile on the NME Radar blog.
Summer Camp have a new duo snapping at their lo-fi heels: Cults. The boyfriend / girlfriend pair hail from Brooklyn and have had the blogosphere in a lather over the last few months. We talked to them for a Radar feature back in April.
Montreal's Suuns have been hogging the NME stereo a bit of late; their layered electronic soundscapes call to mind LCD or TVOTR but they keep bouncing off in new directions to avoid proper categorisation. Have a listen on MySpace.
First profiled in Radar back in October, Tribes have done their best to avoid media attention and build a traditional buzz, but their mid-90s indie rock (think Pixies, Pavement) reached us soon enough.
Vondelpark has no MySpace and wouldn't send us a picture (there's always one "enigmatic" one, every year) but he hails from Surrey and has certain people all worked up over his dreamy electronica. Have a listen on the Hype Machine.
Outraging as many people as they turn on, LA rap crew Odd Future are rude, crude, and getting their swag on. Check Jaimie Hodgson's Radar blog to hear 10 more acts for 2011 that didn't quite make the cut.