Madonna in the video for 'Sorry' in February 2006, which was directed by long-time collaborator Jamie King and picked up thematically from where 'Hung Up' left off.
Madonna is supporting Hillary Clinton's bid to be US president, although she's said she'd be supporting Al Gore if he was running, because of his environmental awareness work.
Madonna's new album 'Hard Candy' is out on April 28, and a world tour is being lined up for later in the year, rumoured to be starting on September 11 at London's Wembley Stadium.
The year 2008 has already been a busy one for Madonna. She released her directorial debut 'Filth And Wisdom' in February, releases her new studio album 'Hard Candy' in two weeks. The star has also just finished producing 'I Am Because We Are', a documentary on orphans in Malawi.
Madonna's new album 'Hard Candy' marks - along with a compilation release in the future - the end of her traditional record contract with Warner Bros. Last year she signed a $120 million deal with concert promoters Live Nation.
Madonna on her massive Confessions Tour, which opened in Los Angeles on May 21, 2006 and wrapped up four months later in September in Tokyo.
Madonna duuring her 2006 Confessions Tour, which drew criticism from various religious groups due to her on-stage representation of the crucifixion.
Madonna on her 1996 Confessions Tour, which saw her play a total of 60 shows to 1.2 million people across North America, Europe, and Japan, making it highest grossing tour ever for a female artist.
Madonna's best track from 1995, when this shot was taken, was arguably her cover of Marvin Gaye's 'I Want You', which she recorded with Massive Attack.
Madonna pictured in 1995, the year she starred in 'Four Rooms', and released 'Something To Remember', a collection of her ballads.
In 1990, when this picture was taken, Madonna starred in the film adaptation of 'Dick Tracy', and released hits compilation 'The Immaculate Collection' in November.
Madonna in 1989, the year her fourth album 'Like A Prayer' was released, which to date has shifted in excess of 12 million copies worldwide.
Madonna's first single was 'Everybody', released almost 26 years ago to this day, on April 24, 1982.
Was Madonna successful in the UK? We'll let you be the judge of that when we tell you she's sold over 3.6 million copies of 'The Immaculate Collection' and had 61 (that's sixty-one) Top Ten singles.
As of 2008, Madonna's been in the music business for 26 years. Since her debut in 1982 she's become officially the world's most successful female musician, according to Guinness World Records.
'Hard Candy' sees Madonna move into a more hip-hop direction, or as producer Timbaland said: "It's kinda like 'Holiday' with an R&B groove."
'Hard Candy' boasts a whole host of guest collaborators, including Justin Timberlake, Pharrell Williams and Kanye West.
Madonna's new album 'Hard Candy' hits the shops on April 28, but for the week leading up to the release she'll be letting fans download a different song each day, including 'Candy Shop', 'Miles Away', 'Give It 2 Me', 'Heartbeat', 'Beat Goes On', 'Devil Wouldn't Recognize You' and 'She's Not Me'.
As Madonna's 11th studio album 'Hard Candy' is set to be released, we take a look back at the material girl's best moments over the ages. Keep clicking for many more Madonna shots.