Madonna in the video for 'Sorry' in February 2006, which was directed by long-time collaborator Jamie King and picked up thematically from where 'Hung Up' left off.
Madonna is supporting Hillary Clinton's bid to be US president, although she's said she'd be supporting Al Gore if he was running, because of his environmental awareness work.
Madonna's new album 'Hard Candy' marks - along with a compilation release in the future - the end of her traditional record contract with Warner Bros. Last year she signed a $120 million deal with concert promoters Live Nation.
Madonna duuring her 2006 Confessions Tour, which drew criticism from various religious groups due to her on-stage representation of the crucifixion.
Madonna's best track from 1995, when this shot was taken, was arguably her cover of Marvin Gaye's 'I Want You', which she recorded with Massive Attack.
In 1990, when this picture was taken, Madonna starred in the film adaptation of 'Dick Tracy', and released hits compilation 'The Immaculate Collection' in November.
Was Madonna successful in the UK? We'll let you be the judge of that when we tell you she's sold over 3.6 million copies of 'The Immaculate Collection' and had 61 (that's sixty-one) Top Ten singles.
As of 2008, Madonna's been in the music business for 26 years. Since her debut in 1982 she's become officially the world's most successful female musician, according to Guinness World Records.
Madonna's new album 'Hard Candy' hits the shops on April 28, but for the week leading up to the release she'll be letting fans download a different song each day, including 'Candy Shop', 'Miles Away', 'Give It 2 Me', 'Heartbeat', 'Beat Goes On', 'Devil Wouldn't Recognize You' and 'She's Not Me'.
The world’s defining voice in music and pop culture since 1952.