Based on Lisa Genova’s 2007 novel, Still Alice is dominated by a magnificent, Oscar-winning performance from Julianne Moore. She plays Alice Howland, a linguistics professor and mother who is diagnosed with early-onset Alzheimer’s disease after her 50th birthday. Moore – who spent time talking to sufferers of the disease and doctors who treat it – captures the anger and frustration high-achieving Alice feels as she fumbles over words and forgets appointments. As Alice’s identity is stripped away, Moore’s portrayal of her deterioration is intensely vivid. Other characters – including Alice’s husband John (Alec Baldwin) – may be under-developed, but the climactic interaction between Alice and youngest daughter Lydia (Twilight‘s Kristen Stewart) is immensely affecting.